Modification to a Commercial Immunoradiometric Assay Permitting Intraoperative Monitoring of Parathyroid Hormone Levels
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چکیده
منابع مشابه
A Comprehensive Review of Intraoperative Parathyroid Hormone Monitoring A Comprehensive Review of Intraoperative Parathyroid Hormone Monitoring
Intraoperative parathyroid hormone monitoring (IOPTH) has changed the surgical approach to primary hyperparathyroidism (PHPT). The traditional approach for the treatment of PHPT is a bilateral neck exploration (BNE), which entails the identification of all parathyroid glands and resection of the abnormal glands. However, with the advent of improved surgical adjuncts, including preoperative ultr...
متن کاملIntraoperative monitoring of parathyroid hormone with a rapid automated assay that is commercially available.
The Mayo Clinic was one of the first institutions to develop an in-house rapid parathyroid hormone (PTH) assay that used homegrown antibodies to monitor plasma PTH levels during parathyroidectomy. This PTH assay is economical, but it requires highly trained technologists and an experienced laboratory director and it is difficult to perform in the operating suite. We sought a fully automated mul...
متن کاملIntraoperative intact parathyroid hormone level monitoring as a guide to parathyroid reimplantation after thyroidectomy.
OBJECTIVE The goal of this study was to determine whether intraoperative intact parathyroid hormone (IOiPTH) levels can predict the functional status of remaining parathyroids at the end of total thyroidectomy and thereby be a guide for parathyroid autotransplantation when glands are deemed not functional. STUDY DESIGN Prospective study involving 23 patients undergoing either total thyroidect...
متن کاملClinical usefulness of intraoperative parathyroid hormone monitoring for primary hyperparathyroidism
Purpose The availability of intraoperative parathyroid hormone (IOPTH) monitoring allows successful focused parathyroidectomy for primary hyperparathyroidism (pHPT). The objective of this study was to report our initial experience in IOPTH monitoring during parathyroid surgery for primary hyperparathyroidsim. Methods Between May 2011 and February 2013, 37 patients underwent focused parathyroi...
متن کاملClinical and laboratory studies of a new immunoradiometric assay of parathyroid hormone-related protein.
Parathyroid hormone-related protein (PTHrP) was measured in plasma by a new immunoradiometric assay (IRMA) from Nichols Institute. The assay is specific for PTHrP and shows excellent parallelism when measuring keratinocyte fluid, samples with high PTHrP content, and PTHrP-supplemented plasma. A precision profile established the assay detection limit at 0.7 pmol/L. PTHrP was unstable in plasma, ...
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ژورنال
عنوان ژورنال: Annals of Clinical Biochemistry: International Journal of Laboratory Medicine
سال: 1990
ISSN: 0004-5632,1758-1001
DOI: 10.1177/000456329002700113